Applications

The intermittent exposure to hypoxia during IHT stimulates epigenetic changes and increased expression of genes that allow adaptation to altitude. The end result of hypoxia adaptation includes improved oxygen, better circulation, improved mitochondrial function, increased tolerance to various stressors and even toxic chemicals, increased antioxidant production and reduced inflammation (Kayser and Verges 2013, Verges, Chacaroun et al. 2015). These adaptive changes can enhance physical and mental capacity, so that the body is better able to cope with a range of stressors and repair and heal cells tissues and organs. (Serebrovskaya, Nikolsky et al. 2011).

IHT increases endothelial production of nitric oxide (NO) while also preventing NO overproduction in the brain and other tissues. The end result is neuroprotection of various pathologies, reduced blood pressure (Lyamina, Lyamina et al. 2011), and a reduction of oxidative stress (Malyshev, Bakhtinia et al. 2001, Manukhina, Downey et al. 2016).